Form: 4

Statement of changes in beneficial ownership of securities

May 24, 2016

FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Micallef Jacob Vincent
   2. Issuer Name and Ticker or Trading Symbol
VOLITIONRX LTD [VNRX] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Scientific Officer
(Last)
(First)
(Middle)
1 SCOTTS ROAD, #24-05 SHAW CENTRE		 3. Date of Earliest Transaction (Month/Day/Year)
05/20/2016
(Street)

SINGAPORE, U0 228208		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/20/2016   M   20,000 A $ 3 48,456 I Borlaug Limited (2)
Common Stock 05/20/2016   F   16,950 (1) D $ 3.54 31,506 I Borlaug Limited (2)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $ 3 05/20/2016   M     20,000 05/25/2012 05/25/2016 Common Stock 20,000 $ 0 0 I Borlaug Limited (3)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Micallef Jacob Vincent
1 SCOTTS ROAD
#24-05 SHAW CENTRE
SINGAPORE, U0 228208		       Chief Scientific Officer  

Signatures

 /s/ Jacob Micallef   05/24/2016
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Represents the aggregate amount of shares of VolitionRx Limited Common Stock ("Common Stock") disposed of in a cashless exercise.
(2) The shares of Common Stock are held directly by Borlaug Limited. Dr. Micallef is a controlling director of Borlaug Limited and has voting and dispositive control over the shares of Common Stock issued to Borlaug Limited upon the exercise of the Option. Dr. Micallef disclaims beneficial ownership of the shares of Common Stock issued upon exercise of the Option, except to the extent of his pecuniary interest.
(3) The Option is held directly by Borlaug Limited. Dr. Micallef is a controlling director of Borlaug Limited and has voting and dispositive control over the shares of Common Stock issuable upon the exercise of the Option. Dr. Micallef disclaims beneficial ownership of the shares of Common Stock issuable upon the exercise of the Option, except to the extent of his pecuniary interest.

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